Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745812 | 0.79 | MEN1 (0.50) | SLC6A4KCNQ3KCNQ2CSNK2A1TRPV3 | |
| SCHEMBL21057196 | 0.79 | TSHR (0.49) | SLC6A4MEN1MAPTHPGDKMT2A | |
| SCHEMBL21057197 | 0.79 | TSHR (0.49) | SLC6A4MEN1MAPTHPGDKMT2A | |
| SCHEMBL12009 | 0.78 | P2RX3 (0.41) | KCNQ3KCNQ2CSNK2A1TRPV3NAAA | |
| SCHEMBL6112972 | 0.78 | TSHR (0.39) | CSNK2A1MAPTRORC | |
| SCHEMBL28651200 | 0.77 | PDE4A (0.35) | SLC6A4CSNK2A1HPGD | |
| SCHEMBL425685 | 0.77 | RAB9A (0.50) | SLC6A4MEN1KMT2ABCHEACHE | |
| SCHEMBL6113174 | 0.76 | XDH (0.38) | CSNK2A1MAPTL3MBTL1RORC | |
| SCHEMBL4152456 | 0.76 | PDE4B (0.42) | CSNK2A1MAPTHPGDACHE | |
| SCHEMBL2851014 | 0.76 | ALOX15 (0.37) | CSNK2A1MAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022108849-A1 | HETEROCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS | ARISAN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |