SCHEMBL24465397

SCHEMBL24465397

CCCOC(=O)c1ccc2ccc(C3CO3)cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
ESR1 P03372 3/20 0.46
CHRM1 P11229 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A2 P23975 1/20 0.46
KDR P35968 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
LMNA P02545 2/20 0.43
HRH3 Q9Y5N1 2/20 0.43
HPGD P15428 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HSD17B10 Q99714 1/20 0.42
DRD3 P35462 1/20 0.41
HTR7 P34969 1/20 0.40
STS P08842 1/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24453030 0.84 HRH3 (0.38) ALDH1A1KDM4EHRH3HPGDRAB9A
SCHEMBL706561 0.79 ALDH1A1 (0.65) ALDH1A1ESR1CHRM1TSHRSLC6A2
SCHEMBL16859558 0.74 ESR1 (0.65) ALDH1A1ESR1TSHRTDP1LMNA
SCHEMBL28292306 0.73 LMNA (0.59) ALDH1A1ESR1CHRM1TSHRSLC6A2
SCHEMBL15315290 0.73 KDM4E (0.59) ALDH1A1ESR1CHRM1TSHRSLC6A2
SCHEMBL1499458 0.73 CA1 (0.56) ALDH1A1ESR1TDP1KDM4ELMNA
SCHEMBL20224700 0.73 ALDH1A1 (0.57) ALDH1A1ESR1CHRM1TSHRSLC6A2
SCHEMBL4130114 0.72 MGLL (0.41) ALDH1A1HRH3
SCHEMBL5599708 0.72 ESR1 (0.70) ALDH1A1ESR1CHRM1TSHRSLC6A2
SCHEMBL16412668 0.71 PARP1 (0.59) ALDH1A1TSHRKDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed