Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.57 |
| ▸ | NOS3 | P29474 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488015 | 0.80 | CYP3A4 (0.64) | NOS1CYP1A2CYP3A4PKMALOX15 | |
| SCHEMBL5633860 | 0.77 | ALOX5 (0.59) | F2ALOX5MRGPRX4APPCYP1A2 | |
| SCHEMBL7634874 | 0.77 | ALOX5 (0.53) | F2ALOX5MRGPRX4APPCYP1A2 | |
| SCHEMBL4670284 | 0.77 | ALOX5 (0.46) | NOS1NOS3ALOX5CYP1A2CYP3A4 | |
| Bromide SCHEMBL27590510 | 0.75 | ALOX5 (0.45) | NOS1NOS3ALOX5CYP1A2CYP3A4 | |
| SCHEMBL8276174 | 0.74 | RXRA (0.53) | F2ACHEMRGPRX4APPCYP1A2 | |
| SCHEMBL13814621 | 0.74 | BCHE (0.73) | NOS1NOS3PKMMAPK1MAOB | |
| SCHEMBL4675400 | 0.73 | NOS1 (0.42) | NOS1NOS3NOS2 | |
| SCHEMBL21071006 | 0.73 | APP (0.61) | F2ALOX5MRGPRX4APPCYP1A2 | |
| Hydrochloric Acid SCHEMBL29873726 | 0.73 | BCHE (0.71) | NOS1NOS3PKMMAPK1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006045-A1 | NUCLEIC ACID COMPOUND MANUFACTURING METHOD AND NUCLEIC ACID COMPOUND | FUJIFILM Corporation (JP) | 2022-06-01 | — | — | EP | disclosed |