SCHEMBL7634874

SCHEMBL7634874

Oc1ccc2cc(COc3ccc4cc(O)ccc4c3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
F2 P00734 4/20 0.50
APP P05067 2/20 0.48
MRGPRX4 Q96LA9 1/20 0.47
RAB9A P51151 2/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTGS2 P35354 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HIF1A Q16665 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
NPC1 O15118 2/20 0.46
MAPT P10636 1/20 0.46
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5632422 0.94 ALOX5 (0.60) ALOX5F2APPMRGPRX4CYP1A2
SCHEMBL5633860 0.89 ALOX5 (0.59) ALOX5F2APPMRGPRX4RAB9A
SCHEMBL6350004 0.85 ALOX5 (0.76) ALOX5MRGPRX4RAB9ACYP1A2LMNA
SCHEMBL21071006 0.84 APP (0.61) ALOX5F2APPMRGPRX4RAB9A
SCHEMBL3818205 0.82 ALOX5 (0.77) ALOX5F2MRGPRX4RAB9ACYP1A2
SCHEMBL12938497 0.82 ALOX5 (0.78) ALOX5F2MRGPRX4RAB9ACYP1A2
SCHEMBL10896488 0.81 RAB9A (0.66) ALOX5APPMRGPRX4RAB9ACYP1A2
SCHEMBL14087756 0.79 CYP1A2 (0.48) ALOX5CYP1A2CYP2C19HIF1A
SCHEMBL16681616 0.78 LMNA (0.47) ALOX5CYP1A2LMNAPTGS1HIF1A
SCHEMBL14686116 0.78 LTA4H (0.59) RAB9ACYP1A2HIF1ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1361759-A 6-hydroxy-2-naphthyl carbinol and process for producing the same MITSUBISHI CHEM CORP (JP) 2002-07-31 CN disclosed
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed