SCHEMBL24466816

SCHEMBL24466816

CC(C)c1nc2c(F)c(F)c(F)c(F)c2s1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.39
TLR7 Q9NYK1 1/20 0.39
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12371889 0.71 KDM4E (0.36) TLR8TLR7
SCHEMBL2600746 0.70 TLR8 (0.41) TLR8TLR7
SCHEMBL12320085 0.67
SCHEMBL24476924 0.67 TLR8 (0.36) TLR8TLR7ACACB
SCHEMBL20821463 0.67 KDR (0.42)
SCHEMBL10093847 0.65 TLR8 (0.38) TLR8TLR7
SCHEMBL10093824 0.65 TLR8 (0.38) TLR8TLR7
SCHEMBL21160893 0.64 RAB9A (0.36) TLR8TLR7ACACB
SCHEMBL24476925 0.63 TLR8 (0.36) TLR8TLR7ACACB
SCHEMBL23338518 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130602-A1 INHIBITORS OF C. DIFFICILE SPORE GERMINATION THE BOARDS OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2023-04-27 US disclosed
US-20220173333-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECHNOLOGY CO., LTD (CN) 2022-06-02 US disclosed
EP-4006025-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Technology Co., Ltd. (CN) 2022-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173333-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF KCNH1, OCIAD2, ETFB TLR8 3727/4885TLR7 1693/4885ACACB 2355/4885
US-20230130602-A1 INHIBITORS OF C. DIFFICILE SPORE GERMINATION CDC37, SI, DAD1 TLR8 3386/4885TLR7 4697/4885ACACB 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.