Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569373 | 1.00 | L3MBTL1 (0.51) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL29713159 | 0.88 | TSHR (0.53) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL30569429 | 0.88 | CASP3 (0.50) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL24470885 | 0.88 | CASP3 (0.50) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL24470978 | 0.88 | TSHR (0.53) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL24470977 | 0.88 | EDNRA (0.56) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30569414 | 0.88 | EDNRA (0.56) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24470679 | 0.85 | ALOX15 (0.51) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL29630204 | 0.85 | ALOX15 (0.51) | L3MBTL1POLBF2PTGS2CASP3 | |
| SCHEMBL24485742 | 0.79 | PTGS2 (0.45) | POLBPTGS2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |