Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iopentol SCHEMBL24471 | 0.96 | LMNA (0.82) | LMNACYP2C19HIF1AEGFRSRC | |
| Iopentol SCHEMBL8845316 | 0.96 | LMNA (0.82) | LMNACYP2C19HIF1AEGFRSRC | |
| Iopentol SCHEMBL14740647 | 0.95 | CYP2C19 (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| Iodixanol SCHEMBL28086309 | 0.95 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10058205 | 0.92 | LMNA (0.76) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL5553113 | 0.91 | CYP2C19 (0.91) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL682143 | 0.88 | LMNA (0.80) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL681514 | 0.88 | LMNA (0.84) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3435296 | 0.88 | LMNA (0.76) | LMNACYP2C19HIF1A | |
| Iohexol SCHEMBL37920 | 0.87 | CYP2C19 (1.00) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204086-A | 2,4,6-triiodoisophthalamide derivatives | NYCOMED IMAGING AS (NO) | 1993-04-20 | — | — | US | disclosed |