Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24471013 | 0.74 | SLC26A4 (0.49) | MAOBMAOAACHEMAPT | |
| SCHEMBL20695292 | 0.68 | SLC6A7 (0.51) | MAOBHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20695245 | 0.67 | SLC26A4 (0.59) | MAOBMAOASMN1; SMN2ACHEMAPT | |
| SCHEMBL20695289 | 0.65 | PDCD1LG2 (0.36) | HPGDGAARAB9ASMN1; SMN2MGLL | |
| SCHEMBL17848310 | 0.64 | MAOB (0.77) | MAOBMAOAPARP10ALDH1A1MAPT | |
| SCHEMBL20695396 | 0.62 | PDCD1LG2 (0.37) | HPGDGAASMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL20695389 | 0.62 | PDCD1LG2 (0.37) | NPC1RAB9ASMN1; SMN2MGLLALDH1A1 | |
| SCHEMBL20695449 | 0.62 | PKM (0.43) | GAAMGLLALDH1A1 | |
| SCHEMBL20695303 | 0.62 | MGLL (0.49) | HPGDNPC1RAB9ASMN1; SMN2MGLL | |
| SCHEMBL18633500 | 0.61 | MAOB (0.72) | MAOBMAOAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |