Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449275 | 1.00 | RORC (0.31) | RORC | |
| SCHEMBL2454136 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL2485565 | 0.82 | ENPP2 (0.43) | — | |
| SCHEMBL2779306 | 0.82 | ENPP2 (0.43) | — | |
| SCHEMBL2453736 | 0.82 | ENPP2 (0.47) | — | |
| SCHEMBL2480740 | 0.81 | NQO2 (0.37) | RORC | |
| SCHEMBL2777166 | 0.79 | ENPP2 (0.39) | — | |
| SCHEMBL2777169 | 0.79 | ENPP2 (0.39) | — | |
| SCHEMBL2453428 | 0.78 | HSD11B1 (0.40) | RORC | |
| SCHEMBL2521339 | 0.75 | ENPP2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364088-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | Biogen Idec MA Inc. (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010051030-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | BIOGEN IDEC MA INC. (US) | 2010-05-06 | — | — | WO | disclosed |