Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 2/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.37 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177583 | 0.81 | ALDH1A1 (0.50) | STK17BSTK17ALMNASMN1; SMN2GLP1R | |
| SCHEMBL2463467 | 0.81 | LMNA (0.39) | STK17BSTK17ALMNASMN1; SMN2GLP1R | |
| SCHEMBL12985024 | 0.81 | KMT2A (0.46) | STK17BSTK17ALMNASMN1; SMN2GLP1R | |
| SCHEMBL1937585 | 0.78 | STK17B (0.40) | STK17BSTK17ABCL6ALDH1A1L3MBTL1 | |
| SCHEMBL4535369 | 0.77 | LRRK2 (0.51) | STK17BSTK17AALDH1A1L3MBTL1JAK2 | |
| SCHEMBL12335037 | 0.77 | FGFR1 (0.42) | LATS1LATS2NPC1RAB9ACCNB2 | |
| SCHEMBL1938007 | 0.76 | STK17A (0.50) | STK17BSTK17ABCL6ALDH1A1L3MBTL1 | |
| SCHEMBL16932226 | 0.74 | MAPK8 (0.54) | STK17BSTK17AJAK2 | |
| SCHEMBL2061903 | 0.73 | STK17A (0.40) | STK17BSTK17ALMNAGLP1RLATS1 | |
| SCHEMBL14670668 | 0.72 | STK17B (0.39) | STK17BSTK17ACYP1A2BCL6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | Bayer ScienceCrop AG (DE) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | DPM1, DPYD, POLR1C | STK17B 3187/4885STK17A 2888/4885LMNA 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.