Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649360 | 0.80 | POLB (0.61) | ALDH1A1HPGDHSD17B10POLBCYP1A2 | |
| SCHEMBL24476462 | 0.77 | POLB (0.41) | ALDH1A1HSD17B10POLBCYP1A2CYP3A4 | |
| SCHEMBL24476465 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HSD17B10POLBCYP1A2CYP3A4 | |
| SCHEMBL24476402 | 0.73 | CYP3A4 (0.49) | ALDH1A1HSD17B10POLBCYP1A2CYP3A4 | |
| SCHEMBL13996770 | 0.71 | MEN1 (0.44) | ALDH1A1HPGDHSD17B10GAAPOLB | |
| SCHEMBL24476472 | 0.69 | PDE2A (0.41) | ALDH1A1HPGDPOLBCYP1A2CYP3A4 | |
| SCHEMBL24476814 | 0.65 | CHRNB2 (0.37) | ALDH1A1HPGDGAAKDM4EMAPT | |
| SCHEMBL13847837 | 0.64 | TYMP (0.49) | ALDH1A1HPGDHSD17B10GAAALOX15 | |
| SCHEMBL21637929 | 0.63 | GAA (0.44) | ALDH1A1GAAPOLBALOX15L3MBTL1 | |
| SCHEMBL23895391 | 0.63 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168309-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | INVOX PHARMA LIMITED (GB) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168309-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | STING1, CGAS, MAVS | ALDH1A1 4319/4885HPGD 1914/4885HSD17B10 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.