SCHEMBL24477016

SCHEMBL24477016

CC(C)c1nc2cnccc2n1-c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KA5 O75582 1/20 0.49
ATM Q13315 1/20 0.47
CRBN Q96SW2 1/20 0.46
ALDH1A1 P00352 1/20 0.45
FGFR1 P11362 1/20 0.45
PDE10A Q9Y233 3/20 0.43
CYP1A2 P05177 2/20 0.43
HTT P42858 2/20 0.43
USP2 O75604 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
MAPK1 P28482 1/20 0.41
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PIK3CG P48736 1/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11900493 0.88 RPS6KA5 (0.50) RPS6KA5ATMCRBNALDH1A1FGFR1
SCHEMBL11901438 0.88 RPS6KA5 (0.47) RPS6KA5ATMALDH1A1FGFR1HTT
SCHEMBL24466914 0.88 PDE10A (0.46) CRBNALDH1A1FGFR1PDE10ACYP1A2
SCHEMBL7776583 0.83 RPS6KA5 (0.42) RPS6KA5CRBNPDE10AHTTUSP2
SCHEMBL1102463 0.82 MAPK1 (0.61) CRBNALDH1A1PDE10ACYP1A2HTT
SCHEMBL22507450 0.81 GSR (0.52) CRBNPDE10ACYP1A2HTTMAPK1
SCHEMBL540767 0.80 MAPK1 (0.67) RPS6KA5ATMALDH1A1HTTMAPK1
SCHEMBL11901855 0.77 AOC3 (0.43) RPS6KA5ALDH1A1FGFR1PDE10ACYP1A2
SCHEMBL11901111 0.77 TDP1 (0.47) ALDH1A1HTTMAPK1TP53
SCHEMBL19851076 0.76 RPS6KA5 (0.52) RPS6KA5ATMALDH1A1FGFR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173333-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECHNOLOGY CO., LTD (CN) 2022-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173333-A1 HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF KCNH1, OCIAD2, ETFB RPS6KA5 4296/4885ATM 3812/4885CRBN 4676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.