SCHEMBL1102463

SCHEMBL1102463

CC(C)c1nc2ccccc2n1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.61
HTT P42858 1/20 0.61
CRBN Q96SW2 1/20 0.54
PIK3CD O00329 1/20 0.54
PIK3CA P42336 1/20 0.54
PIK3CB P42338 1/20 0.54
PIK3CG P48736 1/20 0.54
CYP1A2 P05177 3/20 0.53
PDE10A Q9Y233 3/20 0.53
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152539 0.90 CRBN (0.53) MAPK1HTTCRBNPIK3CDPIK3CA
SCHEMBL22507273 0.88 CRBN (0.54) MAPK1HTTCRBNPIK3CDPIK3CA
SCHEMBL6461042 0.87 ESR2 (0.57) MAPK1HTTCRBNPIK3CDPIK3CA
SCHEMBL14499601 0.87 CRBN (0.53) MAPK1HTTCRBNPIK3CDPIK3CA
SCHEMBL11901863 0.86 MAPK1 (0.57) MAPK1HTTCRBNCYP1A2PDE10A
SCHEMBL11901164 0.86 MAPK1 (0.57) MAPK1HTTCRBNCYP1A2PDE10A
SCHEMBL10897042 0.86 MAPK1 (0.57) MAPK1HTTCRBNCYP1A2PDE10A
SCHEMBL11901680 0.86 MAPK1 (0.57) MAPK1HTTCRBNCYP1A2PDE10A
SCHEMBL22507450 0.84 GSR (0.52) MAPK1HTTCRBNPIK3CDPIK3CA
SCHEMBL22507268 0.84 CRBN (0.51) MAPK1HTTCRBNPIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11618757-B2 Polycyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2023-04-04 US disclosed
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF CHANGCHUN HYPERIONS TECH CO LTD (CN) 2023-01-26 US disclosed
EP-4101841-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF Changchun Hyperions Technology Co., Ltd. (CN) 2022-12-14 EP disclosed
US-20210351364-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE SK MATERIALS JNC CO., LTD. (KR) 2021-11-11 US disclosed
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-05-11 US disclosed
US-20210135119-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2021-05-06 US disclosed
US-20210119139-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-04-22 US disclosed
US-10968230-B2 Spiro-structured compound and organic electronic device comprising same LG CHEM, LTD. 2021-04-06 US disclosed
US-20210020852-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed
US-10892419-B2 Space-through charge transfer compound, and organic light emitting diode and display device using the same LG DISPLAY CO., LTD. (KR) 2021-01-12 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed
US-20090200926-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-08-13 US disclosed
US-20090153039-A1 Green electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-18 US disclosed
EP-2067766-A1 Green electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-06-10 EP disclosed
EP-2067767-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-06-10 EP disclosed
US-20070142369-A1 Combination of an H3 antagonist/inverse agonist and an appetite suppressant SCHERING CORPORATION 2007-06-21 US disclosed
US-20070142369-A1 Combination of an H3 antagonist/inverse agonist and an appetite suppressant SCHERING CORPORATION 2007-06-21 US disclosed
US-20070107835-A1 ETHYNYL CONTAINING ELECTRON TRANSPORT DYES AND COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 US disclosed
US-7192657-B2 Ethynyl containing electron transport dyes and compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10892419-B2 Space-through charge transfer compound, and organic light emitting diode and display device using the same NLRP1, NLRP3, CYBA MAPK1 2890/4885HTT 2976/4885CRBN 895/4885
US-20070142369-A1 Combination of an H3 antagonist/inverse agonist and an appetite suppressant CNR2, GPR119, GLP1R MAPK1 3216/4885HTT 267/4885CRBN 3662/4885
US-20210119139-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME C1S, CRY1, SOS1 MAPK1 1127/4885HTT 1613/4885CRBN 493/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 MAPK1 640/4885HTT 2108/4885CRBN 1419/4885
US-20210135119-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 MAPK1 4873/4885HTT 815/4885CRBN 2694/4885
US-10968230-B2 Spiro-structured compound and organic electronic device comprising same ESR1, OR10J3, ERG MAPK1 3296/4885HTT 2875/4885CRBN 2960/4885
US-20090200926-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same NQO1, NDUFS2, NDUFS5 MAPK1 1347/4885HTT 1693/4885CRBN 2909/4885
US-11618757-B2 Polycyclic compound and organic light emitting element comprising same CRY1, CRY2, PER2 MAPK1 1964/4885HTT 3623/4885CRBN 1307/4885
US-20230025656-A1 TRIARYLAMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF TRDMT1, TCF4, TRMT1 MAPK1 4053/4885HTT 114/4885CRBN 4668/4885
US-20090153039-A1 Green electroluminescent compounds and organic electroluminescent device using the same C1S, ACSL3, CCNL2 MAPK1 1635/4885HTT 1153/4885CRBN 3921/4885
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same DCX, TERT, TELO2 MAPK1 2136/4885HTT 830/4885CRBN 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.