Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24759678 | 0.85 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL22628155 | 0.79 | DHFR (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL19508069 | 0.76 | P2RX3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL21076527 | 0.75 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL22725611 | 0.75 | GABRP (0.37) | — | |
| SCHEMBL24730694 | 0.74 | NOS3 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL23231054 | 0.74 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL12749938 | 0.74 | NOS3 (0.55) | NOS3NOS1NOS2 | |
| SCHEMBL12749937 | 0.73 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL12749936 | 0.73 | NOS3 (0.36) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168313-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168313-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | WEE1, WEE2, VHL | NOS3 3249/4885NOS1 3235/4885NOS2 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.