Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24482981 | 0.89 | MAPK8 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL8687098 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL24482987 | 0.84 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL24482982 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL24482985 | 0.80 | CFTR (0.45) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL24482887 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL22022202 | 0.79 | PLA2G2A (0.52) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL21478268 | 0.77 | PABPC1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10PABPC1 | |
| SCHEMBL6300552 | 0.76 | ABCB11 (0.53) | HSD17B10MAPTKMT2AMAPK8 | |
| SCHEMBL5234885 | 0.75 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111222-A1 | AMIDE DERIVATIVE SERVING AS PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST, AND USE THEREOF | 安润医药科技（苏州）有限公司 | 2022-06-02 | — | — | WO | disclosed |