SCHEMBL24486804

SCHEMBL24486804

N=C(N)NCNC(=S)OCc1cc2ccccc2oc1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
ADAM17 P78536 1/20 0.43
MAOB P27338 5/20 0.41
MAOA P21397 2/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LGALS3 P17931 2/20 0.39
LGALS9 O00182 1/20 0.39
LGALS8 O00214 1/20 0.39
LGALS2 P05162 1/20 0.39
LGALS1 P09382 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21171787 0.92 MAOB (0.44) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL21533708 0.80 MMP2 (0.48) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL24487222 0.80 MMP2 (0.44) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL24487267 0.79 MMP2 (0.52) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL24487275 0.79 MAOB (0.47) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL21171899 0.78 AKR1B10 (0.43) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL21172147 0.78 MMP2 (0.46) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL24487263 0.78 MAOB (0.49) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL24486985 0.78 MMP2 (0.43) MMP2MMP9ADAM17MAOBMAOA
SCHEMBL21172140 0.78 MAOB (0.44) MMP2MMP9ADAM17MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352325-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2022-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352325-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, ST3GAL3 MMP2 790/4885MMP9 2681/4885ADAM17 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.