Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578218 | 0.74 | EPHX1 (0.38) | ALDH1A1EPHX2 | |
| SCHEMBL1578220 | 0.74 | EPHX1 (0.38) | ALDH1A1EPHX2 | |
| SCHEMBL1934904 | 0.74 | GAA (0.43) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL30075988 | 0.72 | NAAA (0.42) | ALDH1A1ATMNAAAGAAMAPK1 | |
| SCHEMBL533667 | 0.72 | EPHX2 (0.62) | L3MBTL1EPHX2 | |
| SCHEMBL533822 | 0.71 | EPHX2 (0.45) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL14973388 | 0.69 | EPHX2 (0.40) | MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL12496107 | 0.68 | NAAA (0.39) | KMT2AALDH1A1MAPTEPHX2NAAA | |
| SCHEMBL12832497 | 0.68 | EPHX2 (0.50) | L3MBTL1EPHX2 | |
| SCHEMBL6452242 | 0.67 | EPHX2 (0.52) | MEN1KMT2AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364311-A1 | TROPANE UREA DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF AS MODULATORS OF THE ACTIVITY OF 11BETAHSD1 | SANOFI (FR) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010049635-A1 | TROPANE UREA DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF AS MODULATORS OF THE ACTIVITY OF 11BETAHSD1 | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | WO | disclosed |