Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778752 | 0.90 | SIGMAR1 (0.70) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL8213555 | 0.86 | OPRL1 (0.67) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL10287607 | 0.85 | OPRM1 (0.63) | OPRL1DRD2OPRM1CCR3 | |
| Hydrochloric Acid SCHEMBL29777982 | 0.84 | POLB (0.68) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL4684452 | 0.83 | DRD2 (0.56) | SIGMAR1DRD2OPRM1MEN1KMT2A | |
| SCHEMBL2059079 | 0.83 | OPRL1 (0.68) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL1307928 | 0.83 | OPRL1 (0.65) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL3867146 | 0.82 | OPRM1 (0.55) | OPRL1SIGMAR1DRD2OPRM1 | |
| Hydrochloric Acid SCHEMBL28638282 | 0.82 | OPRL1 (0.54) | OPRL1SIGMAR1POLBDRD2OPRM1 | |
| SCHEMBL9370237 | 0.81 | SIGMAR1 (0.72) | OPRL1SIGMAR1POLBDRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325443-B1 | PROCESS FOR PREPARING PRIDOPIDINE | Prilenia Neurotherapeutics Ltd (IL) | 2022-06-08 | — | — | EP | disclosed |