⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294254 | 0.73 | — | — | |
| SCHEMBL12778740 | 0.71 | — | — | |
| SCHEMBL538190 | 0.71 | — | — | |
| SCHEMBL15555797 | 0.71 | — | — | |
| SCHEMBL30986580 | 0.71 | — | — | |
| SCHEMBL21597775 | 0.71 | — | — | |
| SCHEMBL22191743 | 0.69 | XDH (0.49) | — | |
| SCHEMBL22333570 | 0.69 | TRPA1 (0.42) | — | |
| SCHEMBL20578135 | 0.69 | CTSB (0.40) | — | |
| SCHEMBL30518016 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693612-B | Bridging type arylpyrazole type amide compound and its solvent heat one-pot synthesis method and application | 中南民族大学 | 2019-01-08 | — | — | CN | claimed |
| EP-4452254-A2 | TETRAHYDROPYRAZOLOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118613257-A | Tetrahydropyrazolopyrimidines and related analogs for the inhibition of YAP/TAZ-TEAD | 鲁汶大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-118359634-A | Pyrazole derivative and medical use thereof | 正大天晴药业集团股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| WO-2024105553-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | NOVARTIS AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| CN-116969954-B | Tricyclic fused heterocyclic compounds containing lactam and application thereof | 广东省农业科学院农业质量标准与监测技术研究所 | 2023-11-28 | — | — | CN | disclosed |
| CN-116969954-A | Tricyclic fused heterocyclic compounds containing lactam and application thereof | 广东省农业科学院农业质量标准与监测技术研究所 | 2023-10-31 | — | — | CN | disclosed |
| US-20230279016-A1 | Tetrahydropyrazolopyrimidines and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-09-07 | — | — | US | disclosed |
| US-20230279016-A1 | Tetrahydropyrazolopyrimidines and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-09-07 | — | — | US | disclosed |
| US-20230279016-A1 | Tetrahydropyrazolopyrimidines and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-09-07 | — | — | US | disclosed |
| US-20120004421-A1 | Process for the preparation of pyrazole derivatives | BASF SE (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2010105969-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | BASF SE (DE) | 2010-09-23 | — | — | WO | disclosed |
| EP-0942904-B1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| CN-1105709-C | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| US-6265430-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| US-20010007876-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | US | disclosed |
| CN-1239953-A | 3-thiocarbamoylpyrazole derivatives as pesticides | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| EP-0942904-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024769-A1 | 3-THIOCARBAMOYLPYRAZOLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
| US-4017479-A | Cationic indazole-azo-5-amino pyrazole dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |