SCHEMBL244918

SCHEMBL244918

COc1cc(NCCCS(=O)(=O)O)cc(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
POLB P06746 2/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
SLC2A1 P11166 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27677191 0.98 KMT2A (0.41) KMT2APOLBMTNR1AMTNR1BSLC2A1
Water SCHEMBL20853621 0.97 KMT2A (0.41) KMT2APOLBMTNR1AMTNR1BSLC2A1
SCHEMBL5587045 0.97 KMT2A (0.42) KMT2APOLBMTNR1AMTNR1BSLC2A1
SCHEMBL2111043 0.91 MTNR1A (0.39) KMT2APOLBMTNR1AMTNR1BSLC2A1
SCHEMBL2498356 0.86 MTNR1A (0.59) KMT2APOLBMTNR1AMTNR1BLMNA
SCHEMBL4143235 0.85 MTNR1A (0.39) KMT2APOLBMTNR1AMTNR1BLMNA
SCHEMBL917492 0.84 GAA (0.59) KMT2ASLC2A1ALDH1A1PKMGAA
SCHEMBL4614538 0.81 SLC2A1 (0.37) KMT2APOLBSLC2A1LMNASMN1; SMN2
SCHEMBL918087 0.78 SLC2A1 (0.55) KMT2ASLC2A1ALDH1A1SMN1; SMN2MEN1
SCHEMBL1823998 0.78 THRB (0.44) ALDH1A1MAPTSMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104076158-B A kind of test kit for measuring HDL-C 深圳市新产业生物医学工程股份有限公司 2016-08-17 CN claimed
US-20020182600-A1 Method for assaying biological and other constituents using synthetic nucleounits in lateral flow, liquid, and dry chemistry techniques SMITH JACK V (US) 2002-12-05 US claimed
US-12498366-B2 Measurement method for fibroblast growth factor-23 by forming immunocomplexes CANON MEDICAL DIAGNOSTICS CORPORATION (JP) 2025-12-16 US disclosed
EP-3995586-B1 GLYCOSYLATED PROTEIN ASSAY REAGENT CONTAINING PROTEASE STABILIZER INCREASING REDOX POTENTIAL OF FERROCYANIDE, METHOD FOR ASSAYING GLYCOSYLATED PROTEIN, METHOD FOR PRESERVING GLYCOSYLATED PROTEIN ASSAY REAGENT, AND METHOD FOR STABILIZING GLYCOSYLATED PROTEIN ASSAY REAGENT NAGASE DIAGNOSTICS CO LTD (JP) 2025-11-05 EP disclosed
US-12264356-B2 Method for determining sensitivity to SGLT2 inhibitor and sensitivity marker for SGLT2 inhibitor NIHON UNIVERSITY (JP) 2025-04-01 US disclosed
US-12168795-B2 Method for measuring cholesterol in low-density lipoprotein, measurement reagent, and measurement kit HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-12-17 US disclosed
US-20240402163-A1 Method for Measuring Fibroblast Growth Factor-23 and Reagent Therefor HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-12-05 US disclosed
US-12092637-B2 Method for measuring fibroblast growth factor-23 and reagent therefor HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2024-09-17 US disclosed
EP-3492600-B1 METHOD FOR MEASURING GLYCATED HEMOGLOBIN HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO LTD (JP) 2024-04-24 EP disclosed
US-20230358767-A1 METHOD FOR REDUCING MEASUREMENT ERROR SEKISUI MEDICAL CO., LTD. (JP) 2023-11-09 US disclosed
WO-2023190087-A1 ENHACEMENT OF ACCURACY WHEN MEASURING HIGH-CREATININE-VALUE SPECIMEN 東洋紡株式会社 2023-10-05 WO disclosed
US-5328832-A Hydrolysis of triglycerides, measurement of fatty acids, heat treatment and freeze drying IATRON LABORATORIES, INC. (JP) 1994-07-12 US disclosed
EP-0337005-B1 Lyophilizate of an aqueous solution of triglyceride substrate for determination of lipase IATRON LAB (JP) 1993-12-08 EP disclosed
US-5156955-A Used as enzyme for catalyzing oxidation reaction of nucleoside OTSUKA FOODS CO., LTD. (JP) 1992-10-20 US disclosed
US-5082769-A Hydrolysis IATRON LABORATORIES, INC. (JP) 1992-01-21 US disclosed
EP-0353311-A1 NUCLEOSIDE OXIDASE AND ANALYTICAL METHOD USING SAME OTSUKA FOODS CO., LTD. (JP) 1990-02-07 EP disclosed
EP-0337005-A1 Lyophilizate of an aqueous solution of triglyceride substrate for determination of lipase IATRON LABORATORIES, INC. (JP) 1989-10-18 EP disclosed
EP-0267247-A1 PROCESS AND REAGENT FOR DETECTING HEART LESIONS OR DISEASES Roche Diagnostics GmbH (DE) 1988-05-18 EP disclosed
WO-1987006619-A1 PROCESS AND REAGENT FOR DETECTING HEART LESIONS OR DISEASES BOEHRINGER MANNHEIM GMBH (DE) 1987-11-05 WO disclosed
EP-0243901-A1 Process and reagent for the detection of heart lesions or heart diseases Roche Diagnostics GmbH (DE) 1987-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230358767-A1 METHOD FOR REDUCING MEASUREMENT ERROR CAT, MPO, UCHL1 KMT2A 1904/4885POLB 595/4885MTNR1A 2535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.