Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3156511 | 0.97 | LTA4H (0.52) | SNCALTA4HMEN1KMT2AL3MBTL1 | |
| Water SCHEMBL8527845 | 0.97 | LTA4H (0.52) | SNCALTA4HMEN1KMT2AL3MBTL1 | |
| Iodide SCHEMBL7909299 | 0.97 | LTA4H (0.52) | SNCALTA4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL8372239 | 0.92 | LTA4H (0.47) | SNCALTA4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL8375288 | 0.92 | LTA4H (0.47) | SNCALTA4HMEN1KMT2AL3MBTL1 | |
| Bromide SCHEMBL1044358 | 0.87 | LTA4H (0.54) | SNCALTA4HSMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL28338224 | 0.86 | CALM1 (0.43) | SNCAMEN1KMT2ASIGMAR1SMN1; SMN2 | |
| Iodide SCHEMBL1047429 | 0.83 | LTA4H (0.54) | SNCALTA4H | |
| Hydrochloric Acid SCHEMBL1046793 | 0.83 | LTA4H (0.54) | SNCALTA4H | |
| SCHEMBL8375290 | 0.83 | SNCA (0.42) | SNCALTA4HMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248161-B1 | Preparation of permanent color inks from water-soluble colorants using specific phosphonium salts | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | claimed |
| US-6210816-B1 | Translucent xerographic recording substrates | XEROX CORPORATION | 2001-04-03 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-6086661-A | (A)IMIDAZOLINIUM QUATERNARY SALT, (B) PHOSPHONIUM QUATERNARY SALT, OR (C) AN AMMONIUM QUATERNARY SALT; A PAPER-CURL REDUCING COMPOUND; DYE; STABILIZERS, BIOCIDE, WATER SOLUBLE SALT | XEROX CORPORATION (US) | 2000-07-11 | — | — | US | claimed |
| US-5760809-A | INK JET PRINTING | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| US-5665802-A | REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-09-09 | — | — | US | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0615853-B1 | Recording sheets containing phosphonium compounds | XEROX CORP (US) | 1996-10-16 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0477472-B1 | Process for the preparation of cyclic carbonates | RUETGERSWERKE AG (DE) | 1995-12-13 | — | — | EP | claimed |
| US-5153333-A | Reacting epoxy compound with carbon dioxide in presence of quaternary phosphonium halide catalyst | RUTGERSWERKE AG (DE) | 1992-10-06 | — | — | US | claimed |
| WO-2026087965-A1 | COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2025200154-A1 | TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-10-02 | — | — | WO | disclosed |
| US-20240309240-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2024-09-19 | — | — | US | disclosed |
| US-5153333-A | Reacting epoxy compound with carbon dioxide in presence of quaternary phosphonium halide catalyst | RUTGERSWERKE AG (DE) | 1992-10-06 | — | — | US | disclosed |
| EP-0477472-A1 | Process for the preparation of cyclic carbonates | Bakelite AG (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0350958-A2 | Improved polyimide and polyimide film and manufacturing method thereof | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-17 | — | — | EP | disclosed |