Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18997799 | 0.76 | EPHX2 (0.44) | PIK3C3EPHX2 | |
| SCHEMBL24040316 | 0.74 | PIK3C3 (0.41) | PIK3C3 | |
| SCHEMBL8206746 | 0.66 | ADAM17 (0.39) | — | |
| SCHEMBL19049573 | 0.65 | EPHX2 (0.46) | PIK3C3EPHX2 | |
| SCHEMBL19001361 | 0.63 | CHRNB2 (0.58) | EPHX2 | |
| SCHEMBL24775950 | 0.61 | PARP1 (0.36) | — | |
| SCHEMBL19275757 | 0.61 | CHRNB2 (0.44) | PIK3C3 | |
| SCHEMBL23449294 | 0.60 | PIK3C3 (0.40) | PIK3C3 | |
| SCHEMBL19275747 | 0.58 | PIK3C3 (0.43) | PIK3C3 | |
| SCHEMBL17069026 | 0.56 | EPHX2 (0.58) | PIK3C3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175788-A1 | 6-HETEROCYCLYL-4-MORPHOLIN-4-YLPYRIDINE-2-ONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES | SPRINT BIOSCIENCE AB (SE) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175788-A1 | 6-HETEROCYCLYL-4-MORPHOLIN-4-YLPYRIDINE-2-ONE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER AND DIABETES | CDK6, IL6, CDK4 | PIK3C3 4621/4885EPHX2 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.