Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | HTR2A | P28223 | 8/20 | 0.53 |
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29586776 | 0.99 | EPHX2 (0.54) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL29587475 | 0.85 | HTR2A (0.56) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL24496750 | 0.79 | TRPM8 (0.45) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL20612461 | 0.72 | DRD2 (0.53) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL31235937 | 0.71 | GPR119 (0.63) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL14435759 | 0.70 | HTR2A (0.48) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL5319956 | 0.70 | HTR2A (0.51) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL19289080 | 0.70 | EPHX2 (0.52) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL1690952 | 0.69 | HTR2A (0.50) | EPHX2DRD2HTR2AHTR2CTRPM8 | |
| SCHEMBL19289618 | 0.68 | EPHX2 (0.58) | EPHX2DRD2HTR2AHTR2CTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120048-A1 | HDAC INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-09 | — | — | WO | disclosed |