Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12645018 | 0.85 | CHRNB2 (0.30) | — | |
| SCHEMBL17919395 | 0.78 | LMNA (0.31) | TSHRLMNA | |
| SCHEMBL13149372 | 0.75 | CCR2 (0.31) | TSHRLMNA | |
| SCHEMBL20522668 | 0.75 | ALDH1A1 (0.39) | TSHRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL13363514 | 0.75 | CHRNB2 (0.31) | — | |
| SCHEMBL22528210 | 0.75 | ALDH1A1 (0.39) | TSHRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL5959365 | 0.73 | CHRNB2 (0.30) | — | |
| SCHEMBL14640512 | 0.73 | CHRNB2 (0.30) | — | |
| SCHEMBL8215661 | 0.73 | GABRR1 (0.31) | — | |
| SCHEMBL13939600 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |