Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860742 | 0.76 | CYP1A2 (0.58) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL2176378 | 0.76 | ALDH1A1 (0.45) | CYP1A2CYP2D6DAOALDH1A1HSD17B10 | |
| SCHEMBL27001792 | 0.73 | CYP1A2 (0.50) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL27001802 | 0.73 | CYP1A2 (0.53) | ALOX15CYP1A2CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL356961 | 0.73 | CES2 (0.50) | CYP1A2CYP2D6CYP2C19DAOALDH1A1 | |
| Tenosiprol SCHEMBL9201976 | 0.71 | DAO (0.41) | DAOALDH1A1SMN1; SMN2CES2CES1 | |
| Tenosiprol SCHEMBL2109048 | 0.71 | DAO (0.41) | DAOALDH1A1SMN1; SMN2CES2CES1 | |
| SCHEMBL16615455 | 0.71 | GAA (0.53) | ALOX15CYP1A2CYP2D6CYP2C19DAO | |
| SCHEMBL4164203 | 0.71 | TSHR (0.46) | CYP1A2CYP2D6CYP2C19DAOALDH1A1 | |
| SCHEMBL621714 | 0.70 | ALDH1A1 (0.58) | CYP1A2CYP2D6CYP2C19DAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304630-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | Research Triangle Institute (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192126-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | RESEARCH TRIANGLE INSTITUTE (US) | 2022-09-15 | — | — | WO | disclosed |
| EP-2366704-A1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-21 | — | — | EP | disclosed |