Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501687 | 0.88 | KDM4E (0.46) | KDM4ECYP2C9CYP2C19BDKRB1ACACB | |
| SCHEMBL10130724 | 0.84 | HRH3 (0.51) | KDM4EMEN1KMT2AHRH3CYP2D6 | |
| SCHEMBL14614943 | 0.82 | MEN1 (0.59) | KDM4EMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL24584949 | 0.80 | MEN1 (0.43) | KDM4ECYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL24204794 | 0.80 | GNAI3 (0.51) | MEN1KMT2AACACBACACAHRH3 | |
| SCHEMBL25075011 | 0.79 | HRH3 (0.46) | KDM4ECYP2C9CYP2C19HRH3CYP2D6 | |
| SCHEMBL24206641 | 0.78 | ACACB (0.43) | MEN1KMT2AACACBACACAHRH3 | |
| SCHEMBL24204480 | 0.78 | GNAI3 (0.51) | MEN1KMT2AACACBACACAHRH3 | |
| SCHEMBL25075229 | 0.78 | HRH3 (0.45) | KDM4ECYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL8229259 | 0.78 | ALDH1A1 (0.56) | KDM4EMEN1KMT2AHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |