Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 9/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793197 | 0.85 | NPC1 (0.33) | MAPTNPC1MAOBMAOACA12 | |
| SCHEMBL23695 | 0.80 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL7743517 | 0.79 | MAOB (0.45) | MAPTMAOBPOLBMAOACA12 | |
| SCHEMBL9157249 | 0.77 | KCNH2 (0.37) | — | |
| SCHEMBL2453969 | 0.77 | ADAM17 (0.33) | — | |
| SCHEMBL3841959 | 0.77 | POLB (0.39) | MAPTNPC1MAOBPOLBMAPK1 | |
| SCHEMBL6238419 | 0.76 | JAK2 (0.33) | MAPTMAPK1 | |
| SCHEMBL2455834 | 0.76 | CYP1A2 (0.36) | HSD17B10CYP1A2 | |
| SCHEMBL18694719 | 0.73 | POLB (0.37) | POLBMAPK1HSD17B10CA12CA2 | |
| SCHEMBL8583545 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624092-A | Method for preparing N-diaryl methyl substituted-2-amino furan compound | 湖南理工学院 | 2024-03-01 | — | — | CN | claimed |
| CN-115557926-B | Squaraine compound and preparation method and application thereof | 深圳大学 | 2024-02-06 | — | — | CN | claimed |
| CN-116462616-A | Alkynylamide compounds and application thereof | 暨南大学 | 2023-07-21 | — | — | CN | claimed |
| CN-115557926-A | Squarylium cyanine compound and preparation method and application thereof | 深圳大学 | 2023-01-03 | — | — | CN | claimed |
| US-9975889-B2 | Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-05-22 | — | — | US | claimed |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH | 2017-02-16 | — | — | US | claimed |
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | claimed |
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | claimed |
| US-9220266-B2 | Ketoheteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-29 | — | — | US | claimed |
| EP-2516426-B1 | BIS(DIFLUORMETHYL)PYRAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-09-16 | — | — | EP | claimed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | claimed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | claimed |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | PFIZER INC. | 2008-12-18 | — | — | US | claimed |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | claimed |
| WO-2008012623-A1 | BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008012622-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-0367887-B1 | Herbicidal concentrate | CIBA GEIGY AG (CH) | 1994-03-30 | — | — | EP | claimed |
| US-4933000-A | Herbicidal compound concentrate | CIBA-GEIGY CORPORATION (US) | 1990-06-12 | — | — | US | claimed |
| EP-0367887-A2 | Herbicidal concentrate | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | claimed |
| US-3941829-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | MAPT 3867/4885NPC1 2814/4885MAOB 803/4885 |
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | MAPT 2472/4885NPC1 282/4885MAOB 289/4885 |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | MAPT 3867/4885NPC1 2814/4885MAOB 803/4885 |
| US-20080312271-A1 | AZABENZIMIDAZOLYL COMPOUNDS | AZI2, PAICS, UGT2B7 | MAPT 3948/4885NPC1 651/4885MAOB 79/4885 |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | MAPT 4346/4885NPC1 3778/4885MAOB 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.