Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724930 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| SCHEMBL10256901 | 0.98 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Water SCHEMBL723735 | 0.96 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL723900 | 0.96 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Iodide SCHEMBL11507837 | 0.96 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Water SCHEMBL8939227 | 0.96 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| SCHEMBL3681307 | 0.96 | CHRNA7 (0.60) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Water SCHEMBL8939226 | 0.94 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL28109784 | 0.94 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL2458828 | 0.94 | CHRNA7 (0.58) | CHRNB2CHRNA4CHRNA7APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668227-A | Cyclohexyl-group-containing glycidyl ethers | CIBA-GEIGY CORPORATION (US) | 1997-09-16 | — | — | US | claimed |
| WO-2025100238-A1 | EPOXY COMPOUND AND USE THEREOF | 四国化成工業株式会社 | 2025-05-15 | — | — | WO | disclosed |
| WO-2025062839-A1 | COMPOUND, EPOXY RESIN, CURABLE COMPOSITION, MATERIAL FOR RECYCLING, CURED ARTICLE, METHOD FOR PRODUCING CURED ARTICLE, METHOD FOR PRODUCING DECOMPOSITION PRODUCT, AND DECOMPOSITION METHOD | 株式会社ADEKA | 2025-03-27 | — | — | WO | disclosed |
| CN-113891882-B | Process for producing dihydroisoxazole | 组合化学工业株式会社 | 2024-11-26 | — | — | CN | disclosed |
| US-12065541-B2 | Thermoplastic resin, optical film made therefrom, diol compound, diester compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-08-20 | — | — | US | disclosed |
| CN-114478336-B | Process for producing mercaptophenol compound and intermediate therefor | 组合化学工业株式会社 | 2024-05-14 | — | — | CN | disclosed |
| US-20240084065-A1 | NOVEL COMPOUND, AND CURABLE RESIN COMPOSITION CONTAINING SAID COMPOUND | ADEKA CORPORATION (JP) | 2024-03-14 | — | — | US | disclosed |
| EP-4289837-A1 | NOVEL COMPOUND, AND CURABLE RESIN COMPOSITION CONTAINING SAID COMPOUND | ADEKA CORPORATION (JP) | 2023-12-13 | — | — | EP | disclosed |
| CN-113950500-B | Thermoplastic resin, optical film comprising the same, diol compound, and diester compound | 三菱化学株式会社 | 2023-11-03 | — | — | CN | disclosed |
| EP-3988599-B1 | THERMOPLASTIC RESIN, OPTICAL FILM MADE THEREFROM, DIOL COMPOUND, DIESTER COMPOUND | MITSUBISHI CHEM CORP (JP) | 2023-10-18 | — | — | EP | disclosed |
| EP-1323759-A1 | Powder coating composition containing low temperature curable epoxy resin | Kukdo Chemical Co., Ltd. (KR) | 2003-07-02 | — | — | EP | disclosed |
| US-6541541-B2 | Epoxy resin or polyepoxy compound based on glycidol and a bisphenol compound; use as sizing agent for glass fibers; fiber-reinforced resins resistant to thermal coloring and excellent in physical properties | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 2003-04-01 | — | — | US | disclosed |
| EP-1295857-A1 | Aqueous resin composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-20020061941-A1 | Aqueous resin composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA | 2002-05-23 | — | — | US | disclosed |
| EP-0597806-B1 | Novel cyclohexyl substituted glycidylethers | CIBA GEIGY AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-5668227-A | Cyclohexyl-group-containing glycidyl ethers | CIBA-GEIGY CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0645412-A1 | Curable laminating varnishes based on an epoxy resin and dicyandiamide | CIBA-GEIGY AG (CH) | 1995-03-29 | — | — | EP | disclosed |
| EP-0597806-A1 | Novel cyclohexyl substituted glycidylethers | CIBA-GEIGY AG (CH) | 1994-05-18 | — | — | EP | disclosed |
| EP-0559607-A2 | Epoxy resins based on triglycidyl isocyanurate | CIBA-GEIGY AG (CH) | 1993-09-08 | — | — | EP | disclosed |
| EP-0555181-A1 | Storage-stable advanced epoxy resins | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065541-B2 | Thermoplastic resin, optical film made therefrom, diol compound, diester compound | RTF1, RNF31, RNF10 | CHRM3 2295/4885CHRM2 1022/4885CHRM4 2179/4885 |
| US-20240084065-A1 | NOVEL COMPOUND, AND CURABLE RESIN COMPOSITION CONTAINING SAID COMPOUND | PSMC6, CAND1, RBX1 | CHRM3 2075/4885CHRM2 1125/4885CHRM4 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.