Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | RORB | Q92753 | 4/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494111 | 0.83 | RORB (0.50) | KDM4EPKMKMORORBRORC | |
| SCHEMBL269858 | 0.82 | KDM4E (0.53) | KDM4EPKMRORBRORCDHODH | |
| SCHEMBL24508639 | 0.82 | JAK2 (0.51) | KDM4ERORBDHODHALDH1A1HPGD | |
| SCHEMBL24508717 | 0.82 | ALDH1A2 (0.50) | KDM4EPKMKMORORBPIN1 | |
| SCHEMBL14564467 | 0.81 | KDM4E (0.55) | KDM4EPKMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24508643 | 0.78 | RORB (0.67) | KDM4EKMORORBPIN1RORC | |
| SCHEMBL25779068 | 0.78 | FNTA (0.49) | RORBPIN1RORCADORA1 | |
| SCHEMBL1398685 | 0.76 | MAPK14 (0.52) | KDM4EKMOPIN1MAPK14DHODH | |
| SCHEMBL1338215 | 0.76 | KDM4E (0.69) | KDM4EKMOPIN1CTSADHODH | |
| SCHEMBL17843989 | 0.76 | KDM4E (0.49) | KDM4EPKMALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123039-A1 | ALDEHYDE DEHYDROGENASE INHIBITORS AND THEIR THERAPEUTIC USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2022-06-16 | — | — | WO | disclosed |