Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 4/20 | 0.50 |
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.48 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | DDT | P30046 | 1/20 | 0.44 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269858 | 0.83 | KDM4E (0.53) | RORBKDM4EL3MBTL1RORCPKM | |
| SCHEMBL24508717 | 0.83 | ALDH1A2 (0.50) | RORBKMOKDM4ERORCPKM | |
| SCHEMBL24508648 | 0.83 | KDM4E (0.49) | RORBKMORXRARXRBKDM4E | |
| SCHEMBL25779068 | 0.80 | FNTA (0.49) | RORBRORC | |
| SCHEMBL24508643 | 0.80 | RORB (0.67) | RORBKMOKDM4ENPC1RAB9A | |
| SCHEMBL5011865 | 0.75 | KDM4E (0.61) | RORBKDM4ENPC1RAB9AHKDC1 | |
| SCHEMBL25779063 | 0.75 | GPR35 (0.50) | KMOKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL27920106 | 0.74 | KDM4E (0.47) | RORBKDM4ENPC1RAB9ARORC | |
| SCHEMBL25779061 | 0.73 | CDC7 (0.50) | RORBKDM4EL3MBTL1PKM | |
| SCHEMBL71238 | 0.73 | KMO (0.86) | KMORXRARXRBCD74MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010013222-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2010-02-04 | — | — | WO | disclosed |