Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL4953861 | 1.00 | BBOX1 (0.50) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL2451026 | 1.00 | BBOX1 (0.50) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL4929187 | 0.97 | BBOX1 (0.48) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL2457500 | 0.97 | BBOX1 (0.48) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL4926346 | 0.97 | BBOX1 (0.48) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL4926333 | 0.97 | BBOX1 (0.48) | BBOX1CA1CA9FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL2457508 | 0.93 | BBOX1 (0.45) | BBOX1CA1CA9HCAR2 | |
| Fumaric Acid SCHEMBL4929245 | 0.93 | BBOX1 (0.45) | BBOX1CA1CA9HCAR2 | |
| Fumaric Acid SCHEMBL2457505 | 0.93 | BBOX1 (0.45) | BBOX1CA1CA9HCAR2 | |
| Fumaric Acid SCHEMBL4917936 | 0.86 | BBOX1 (0.58) | BBOX1CA1CA9FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115312330-B | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-115312330-A | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| US-5457599-A | Solute for electrolyte is quaternaryammonium salt of caboxylic acid selected from phthalic acid, tetrahydrophthalic acid, maleic acid, hexahydrophthalic acid or an alkyl or nitro substituent of above acids; high temperature stability | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-10-10 | — | — | US | claimed |
| CN-115312330-B | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115312330-A | Super capacitor electrolyte and super capacitor using same | 江苏国泰超威新材料有限公司 | 2022-11-08 | — | — | CN | disclosed |
| EP-1650328-B1 | METHOD FOR FORMING OXIDE FILM ON METAL SURFACE USING IONIC LIQUID, ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORP (JP) | 2016-10-19 | — | — | EP | disclosed |
| EP-2540875-A1 | Electrolytic capacitor including ionic liquid in electrolyte | KANEKA CORPORATION (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8014128-B2 | Method for forming oxide film on metal surface using ionic liquid, electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7746623-B2 | Electrolytic capacitor and electrolyte thereof | KANEKA CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| EP-2003157-A2 | Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications | Air Products and Chemicals, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20080304208-A1 | ELECTROLYTIC CAPACITOR AND ELECTROLYTE THEREOF | KANEKA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-5587871-A | CONTAINING AN ORGANIC POLAR SOLVENT AND AN IONIC SOLUTE WITH FINE PARTICLES OF AN ALUMINOSILICATE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0708452-A1 | Ion-conductive polymer electrolyte, method for producing the electrolyte and capacitors using the electrolyte | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0704871-A1 | Electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0543311-B1 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMICON (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5338472-A | Mixture of g-butyrolactone and ethylene glycol with quaternary alkylammonium phthalate, maleate or benzoate as solute, also with colloidal silica | NIPPON CHEMI-CON CORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0543311-A2 | Electrolytic solution for electrolytic capacitor | NIPPON CHEMI-CON CORPORATION (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4892944-A | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0291074-A2 | Process for producing quaternary salts | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-11-17 | — | — | EP | disclosed |