Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24512662 | 0.86 | MLYCD (0.47) | MLYCDSRD5A2KDM4EALDH1A1ROCK2 | |
| SCHEMBL28777 | 0.82 | MLYCD (0.54) | MLYCDKDM4EALDH1A1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL7476159 | 0.81 | MLYCD (0.53) | MLYCDKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL3303829 | 0.80 | HPGD (0.56) | MLYCDSRD5A2ALDH1A1KMT2AHPGD | |
| SCHEMBL4449884 | 0.80 | MAPT (0.56) | MLYCDKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL19008976 | 0.80 | MLYCD (0.53) | MLYCDKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL16563797 | 0.78 | MLYCD (0.55) | MLYCDALDH1A1ROCK2OPRD1KMT2A | |
| SCHEMBL22531823 | 0.77 | MLYCD (0.57) | MLYCDSRD5A2KDM4EALDH1A1KMT2A | |
| SCHEMBL19533698 | 0.77 | SMN1; SMN2 (0.59) | MLYCDSRD5A2KDM4EALDH1A1KMT2A | |
| SCHEMBL866718 | 0.76 | TSHR (0.64) | SRD5A2ALDH1A1ROCK2OPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | PTDSS1, PTDSS2, SMPD1 | MLYCD 2576/4885SRD5A2 1650/4885KDM4E 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.