Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289824 | 0.77 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17491659 | 0.72 | NPC1 (0.66) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26226874 | 0.71 | NPC1 (0.78) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24513699 | 0.70 | KDM4E (0.63) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15329975 | 0.69 | RAB9A (0.55) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL824419 | 0.67 | NPC1 (0.63) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23076234 | 0.66 | NPC1 (0.54) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29920129 | 0.66 | NPC1 (0.54) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23295693 | 0.65 | NPC1 (0.52) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26227038 | 0.64 | NPC1 (0.62) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122682-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |