SCHEMBL824419

SCHEMBL824419

O=c1nc2oc3ccccc3n2c2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
HPGD P15428 7/20 0.50
HSD17B10 Q99714 6/20 0.50
KDM4E B2RXH2 6/20 0.50
ALDH1A1 P00352 5/20 0.50
NPSR1 Q6W5P4 2/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
RCE1 Q9Y256 1/20 0.44
TSHR P16473 3/20 0.42
MAPK1 P28482 3/20 0.39
USP2 O75604 2/20 0.39
ESR1 P03372 1/20 0.38
POLB P06746 1/20 0.38
ALOX15 P16050 1/20 0.38
PTK2B Q14289 1/20 0.38
MAPT P10636 3/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29889051 0.84 NPC1 (0.47) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL12289824 0.78 NPC1 (1.00) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL29889078 0.76 NPC1 (0.43) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL17491659 0.75 NPC1 (0.66) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL18265534 0.73 NPC1 (0.39) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL13658091 0.73 NPC1 (0.39) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL23076234 0.72 NPC1 (0.54) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL29920129 0.72 NPC1 (0.54) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL23295693 0.71 NPC1 (0.52) NPC1RAB9AHPGDHSD17B10KDM4E
SCHEMBL22472407 0.70 NPC1 (0.48) NPC1RAB9AHPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240147847-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-05-02 US disclosed
EP-4046208-A1 ELECTRONIC DEVICES Merck Patent GmbH (DE) 2022-08-24 EP disclosed
EP-3261759-B1 SELF-HEALING CAPACITOR AND METHODS OF PRODUCTION THEREOF CAPACITOR SCIENCES INC (US) 2020-05-06 EP disclosed
US-10347423-B2 Solid multilayer structure as semiproduct for meta-capacitor CAPACITOR SCIENCES INCORPORATED (US) 2019-07-09 US disclosed
US-RE47117-E1 Compensated in-plane switching mode liquid crystal display CRYSOPTIX K.K. (JP) 2018-11-06 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-20180114641-A1 SOLID MULTILAYER STRUCTURE AS SEMIPRODUCT FOR META-CAPACITOR CAPACITOR SCIENCES INCORPORATED 2018-04-26 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9916931-B2 Energy storage devices and methods of production thereof CAPACITOR SCIENCE INCORPORATED (US) 2018-03-13 US disclosed
US-9852846-B2 Self-healing capacitor and methods of production thereof CAPACITOR SCIENCES INCORPORATED (US) 2017-12-26 US disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
WO-2009130676-A2 COLOR LIQUID CRYSTAL DISPLAY AND COMPENSATION PANEL CRYSOPTIX KK (JP) 2009-10-29 WO disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed
WO-2009037565-A2 COLOUR LIQUID CRYSTAL DISPLAY AND PATTERNED COMPENSATION PANEL CRYSOPTIX K.K. (GB) 2009-03-26 WO disclosed
WO-2008142635-A2 COMPENSATED IN-PLANE SWITCHING MODE LIQUID CRYSTAL DISPLAY CRYSOPTIX KK (GB) 2008-11-27 WO disclosed
WO-2007141025-A2 LIQUID CRYSTAL DISPLAY OPERATING IN A VERTICALLY ALIGNED MODE CRYSOPTIX K.K. (JP) 2007-12-13 WO disclosed
WO-2007122389-A2 BACKLIGHT MODULE AND LIQUID CRYSTAL DISPLAY INCORPORATING THE SAME CRYSOPTIX K.K. (JP) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240147847-A1 ELECTRONIC DEVICES NDUFS4, NDUFS3, NDUFS6 NPC1 4856/4885RAB9A 3358/4885HPGD 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.