SCHEMBL245148

SCHEMBL245148

CCCCCCCCCCCCNCOC

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.57
ALDH1A1 P00352 1/20 0.57
EPHX1 P07099 7/20 0.46
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
S1PR2 O95136 5/20 0.42
S1PR4 O95977 5/20 0.42
S1PR1 P21453 5/20 0.42
S1PR3 Q99500 5/20 0.42
S1PR5 Q9H228 1/20 0.42
THRB P10828 1/20 0.40
HRH4 Q9H3N8 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600861 1.00 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL17623170 0.97
SCHEMBL16090692 0.90
Diethylamine SCHEMBL27825491 0.83 TSHR (0.59) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL14733350 0.82 TSHR (0.48) TSHRALDH1A1EPHX1ADH1BADH1C
Methoxymethane SCHEMBL2150575 0.81 TSHR (0.77) TSHRALDH1A1EPHX1ADH1BADH1C
Methoxymethane SCHEMBL18954805 0.81 TSHR (0.77) TSHRALDH1A1EPHX1ADH1BADH1C
Methoxymethane SCHEMBL2150128 0.81 TSHR (0.77) TSHRALDH1A1EPHX1ADH1BADH1C
Methoxymethane SCHEMBL2149695 0.81 TSHR (0.77) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL27454444 0.81 TSHR (0.87) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230121000-A1 SOLID DOSAGE FORM FOR TRANSMUCOSAL DRUG DELIVERY PRIMO PHARMATECH LLC (US) 2023-04-20 US disclosed
CN-115605207-A Solid dosage form for transmucosal administration 葡默药物技术有限公司(US) 2023-01-13 CN disclosed
US-11419769-B2 Sublingual films SUNOVION PHARMACEUTICALS INC. (US) 2022-08-23 US disclosed
US-20220249465-A1 UNIT DOSAGE FORM FOR TRANSMUCOSAL DRUG DELIVERY OF AN ACTIVE PHARMACEUTICAL INGREDIENT PRIMO PHARMATECH LLC (US) 2022-08-11 US disclosed
CN-114007617-A Unit dosage form for transmucosal administration of pharmaceutically active ingredients 葡瑞慕生物技术有限公司 2022-02-01 CN disclosed
EP-3917502-A1 METHODS OF TREATING A PATIENT HAVING PARKINSON'S DISEASE Sunovion Pharmaceuticals Inc. (US) 2021-12-08 EP disclosed
WO-2021231860-A1 SOLID DOSAGE FORM FOR TRANSMUCOSAL DRUG DELIVERY PRIMO PHARMATECH LLC (US) 2021-11-18 WO disclosed
US-20210322403-A1 SUBLINGUAL APOMORPHINE SUNOVION CNS DEVELOPMENT CANADA ULC (CA) 2021-10-21 US disclosed
US-20210315882-A1 METHODS OF TREATING A PATIENT HAVING PARKINSON'S DISEASE SUNOVION PHARMACEUTICALS INC. 2021-10-14 US disclosed
US-20210205208-A1 METHODS OF TREATING PARKINSON'S DISEASE BY ADMINISTRATION OF APOMORPHINE TO AN ORAL MUCOSA SUNOVION CNS DEVELOPMENT CANADA ULC (CA) 2021-07-08 US disclosed
US-20120082738-A1 MUCOSAL FORMULATION IZUN PHARMACEUTICALS CORPORATION (US) 2012-04-05 US disclosed
US-20120003292-A1 ANTI-INFLAMMATORY DISSOLVABLE FILM KALMAN, JONATHAN, MR. (IL) 2012-01-05 US disclosed
US-8021696-B2 Anti-inflammatory dissolvable film IZUN PHARMACEUTICALS CORPORATION (US) 2011-09-20 US disclosed
WO-2010144817-A1 SUBLINGUAL APOMORPHINE ADAGIO PHARMACEUTICALS LTD. (CA) 2010-12-16 WO disclosed
EP-2068900-A2 FILM-DELIVERING RINSE Izun Pharmaceuticals Corporation (US) 2009-06-17 EP disclosed
EP-2046359-A1 ANTI-INFLAMMATORY DISSOLVABLE FILM Izun Pharmaceuticals Corporation (US) 2009-04-15 EP disclosed
US-20080020027-A1 Film-Delivering Rinse IZUN PHARMACEUTICALS CORP. (US) 2008-01-24 US disclosed
WO-2008011556-A2 FILM-DELIVERING RINSE IZUN PHARMACEUTICALS CORPORATION (US) 2008-01-24 WO disclosed
WO-2007149902-A1 ANTI-INFLAMMATORY DISSOLVABLE FILM IZUN PHARMACEUTICALS CORPORATION (US) 2007-12-27 WO disclosed
US-20070292487-A1 Anti-Inflammatory Dissolvable Film IZUN PHARMACEUTICALS CORPORATION (US) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249465-A1 UNIT DOSAGE FORM FOR TRANSMUCOSAL DRUG DELIVERY OF AN ACTIVE PHARMACEUTICAL INGREDIENT ABCG2, MUC1, SLC2A8 TSHR 4032/4885ALDH1A1 1843/4885EPHX1 2512/4885
US-20210322403-A1 SUBLINGUAL APOMORPHINE HTR5A, OPRL1, SNCA TSHR 1408/4885ALDH1A1 1154/4885EPHX1 1221/4885
US-20230121000-A1 SOLID DOSAGE FORM FOR TRANSMUCOSAL DRUG DELIVERY SLC10A2, MUC1, SLC46A1 TSHR 2919/4885ALDH1A1 1101/4885EPHX1 2229/4885
US-11419769-B2 Sublingual films SNCA, COMT, HTR5A TSHR 241/4885ALDH1A1 2699/4885EPHX1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.