Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845733 | 1.00 | MAPT (0.47) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL17478733 | 0.90 | MAPT (0.49) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL22717265 | 0.86 | PKM (0.55) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL29574368 | 0.86 | PKM (0.55) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL25153559 | 0.85 | ALDH1A1 (0.49) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL22717862 | 0.84 | CYP2C19 (0.48) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL22717354 | 0.83 | POLB (0.48) | MAPTALDH1A1KDM4EGAATSHR | |
| SCHEMBL29574584 | 0.83 | POLB (0.48) | MAPTALDH1A1KDM4EGAATSHR | |
| SCHEMBL22120919 | 0.83 | CYP3A4 (0.40) | MAPTTSHRHSD17B10OPRK1 | |
| SCHEMBL24515322 | 0.81 | MAPT (0.43) | MAPTMAPK1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122987-A1 | ANTHELMINTIC COMPOUNDS COMPRISING A PYRIDINE STRUCTURE | INTERVET INTERNATIONAL B.V. (NL) | 2022-06-16 | — | — | WO | disclosed |