Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727849 | 1.00 | FFAR1 (0.46) | FFAR1CCNT1CDK9PIK3CAMTOR | |
| SCHEMBL13236136 | 0.80 | FFAR1 (0.71) | FFAR1MAP3K5KDM4EMEN1KMT2A | |
| SCHEMBL24518535 | 0.78 | FFAR1 (0.56) | FFAR1CCNT1CDK9MAP3K5KDM4E | |
| SCHEMBL29727858 | 0.78 | FFAR1 (0.56) | FFAR1CCNT1CDK9MAP3K5KDM4E | |
| SCHEMBL12417242 | 0.76 | FFAR1 (0.64) | FFAR1MAP3K5KDM4ENPC1RAB9A | |
| SCHEMBL13780771 | 0.73 | MMP1 (0.54) | FFAR1NPC1RAB9AHPGDLMNA | |
| SCHEMBL24518366 | 0.72 | FFAR1 (0.43) | FFAR1CCNT1CDK9MAP3K5KDM4E | |
| SCHEMBL26794059 | 0.72 | FFAR1 (0.59) | FFAR1MAP3K5KDM4EMEN1KMT2A | |
| SCHEMBL26794066 | 0.68 | FFAR1 (0.58) | FFAR1MAP3K5KDM4EMEN1KMT2A | |
| SCHEMBL9920145 | 0.67 | FFAR1 (0.53) | FFAR1KDM4ERAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820764-B2 | Compound modulating GSK-3 activity | GSK3B, GSK3A, GSKIP | FFAR1 3450/4885CCNT1 409/4885CDK9 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.