SCHEMBL2451964

SCHEMBL2451964

COc1nc(C)nc(N(C(N)=O)S(=O)(=O)c2ccsc2C(=O)O)n1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
FABP4 P15090 10/20 0.39
NPSR1 Q6W5P4 1/20 0.37
EDNRA P25101 3/20 0.36
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
FABP3 P05413 1/20 0.33
FABP2 P12104 1/20 0.33
FABP5 Q01469 1/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793855 0.90 EDNRA (0.41) LMNAEDNRAKMT2AMEN1
SCHEMBL9586075 0.83 EDNRA (0.41) LMNAEDNRAKMT2AMEN1
SCHEMBL9245140 0.82 ALDH1A1 (0.32) KMT2AALDH1A1MEN1
SCHEMBL4284694 0.81 F2 (0.42) FABP4KMT2AMEN1CYP3A4TSHR
SCHEMBL8740196 0.79 KMT2A (0.43) LMNANPSR1KMT2AALDH1A1MEN1
SCHEMBL187348 0.78 MEN1 (0.33) KMT2AMEN1
SCHEMBL10914176 0.78 MEN1 (0.56) KMT2AMEN1CYP3A4
SCHEMBL8848745 0.76 CA1 (0.46) KMT2AALDH1A1MEN1
SCHEMBL9247098 0.75 ALDH1A1 (0.34) FABP4KMT2AALDH1A1MEN1TSHR
SCHEMBL11066173 0.73 TSHR (0.35) KMT2AALDH1A1MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2008-05-15 US claimed
WO-2006009964-A2 NOVEL ESTERS AS USEFUL HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
WO-2006009937-A2 NOVEL ESTERS AS USEFUL BROAD SPECTRUM HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
US-20050282708-A1 Novel esters as useful herbicidal compounds CORET JOEL M 2005-12-22 US claimed
EP-0987945-B1 NEW HERBICIDAL MIXTURES AVENTIS CROPSCIENCE SA (FR) 2001-10-24 EP claimed
US-6239070-B1 REDUCING PHYTOTOXICITY USING 4-BENZOYLISOXAZOLE HERBICIDE;MIXTURE CONTAINING PLANT SAFENING AGENT RHONE-POULENC INC. 2001-05-29 US claimed
EP-0619946-B1 Herbicidal composition for upland farming and weeding method NIHON NOHYAKU CO LTD (JP) 1996-06-05 EP claimed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-12428561-B2 Silicone-polyether copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2025-09-30 US disclosed
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions DOW SILICONES CORPORATION (US) 2025-08-05 US disclosed
US-12344712-B2 Silicone-poly acrylate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2025-07-01 US disclosed
EP-3898782-B1 SILICONE-POLYACRYLATE COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2025-06-25 EP disclosed
US-12269950-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2025-04-08 US disclosed
US-5434121-A Herbicide MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-07-18 US disclosed
EP-0648413-A1 Alkylsiloxanes as adjuvants for agriculture OSi Specialties, Inc. (US) 1995-04-19 EP disclosed
EP-0605533-A1 SYNERGISTIC HERBICIDAL COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 1994-07-13 EP disclosed
WO-1993005655-A1 SYNERGISTIC HERBICIDAL COMPOSITIONS SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed
US-5178662-A 2-/4,6-Dimethoxypyrimidin-2-yloxy/ substituted MITSUI TOATSU CHEMICALS, INC. (JP) 1993-01-12 US disclosed
US-5129937-A Pre- and postemergence; soybean, cotton, corn; injury free MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1992-07-14 US disclosed
EP-0435186-A2 Pyridyloxypyrimidine derivatives, preparation process thereof, and herbicidal compositions containing the same as active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378264-B2 Multifunctional organosilicon compound and related methods, compounds, and compositions MSR1, OXSR1, RIOX2 LMNA 458/4885FABP4 3924/4885NPSR1 60/4885
US-20050282708-A1 Novel esters as useful herbicidal compounds NOTUM, DDT, HDHD5 LMNA 4616/4885FABP4 536/4885NPSR1 2555/4885
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds NOTUM, DDT, HDHD5 LMNA 4611/4885FABP4 493/4885NPSR1 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.