SCHEMBL187348

SCHEMBL187348

COc1nc(C)nc(N(C(N)=O)S(=O)(=O)c2cc(I)ccc2C(=O)O)n1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29080891 0.91 CA1 (0.33) MEN1KMT2A
SCHEMBL4284694 0.85 F2 (0.42) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL2451964 0.78 LMNA (0.40) MEN1KMT2A
SCHEMBL9247098 0.77 ALDH1A1 (0.34) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL15387799 0.77 TP53 (0.32) MEN1KMT2A
SCHEMBL8740196 0.77 KMT2A (0.43) MEN1KMT2AF2
SCHEMBL8848745 0.76 CA1 (0.46) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL10914176 0.75 MEN1 (0.56) MEN1KMT2A
SCHEMBL4291049 0.73 MEN1 (0.38) MEN1KMT2AF2PRSS1PRSS2
SCHEMBL7793855 0.73 EDNRA (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240365781-A1 SYNERGISTICALLY EFFECTIVE HERBICIDE COMPOSITION COMPRISING PELARGONIC ACID AND FLAZASULFURON BELCHIM CROP PROTECTION NV (BE) 2024-11-07 US disclosed
US-20240108008-A1 COMPOSITIONS COMPRISING MESOSULFURON-METHYL AND TEHP BAYER AKTIENGESELLSCHAFT (DE) 2024-04-04 US disclosed
EP-4275497-A2 SYNERGISTICALLY EFFECTIVE HERBICIDE COMPOSITION COMPRISING PELARGONIC ACID AND FLAZASULFURON Certis Belchim NV (BE) 2023-11-15 EP disclosed
EP-3697214-B1 SYNERGISTICALLY EFFECTIVE HERBICIDE COMPOSITION COMPRISING PELARGONIC ACID AND FLAZASULFURON CERTIS BELCHIM NV (BE) 2023-09-27 EP disclosed
CN-116568137-A Compositions comprising mesosulfuron and TEHP 拜耳公司 2023-08-08 CN disclosed
US-20230136215-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2023-05-04 US disclosed
EP-3488696-B1 HERBICIDAL COMBINATION WITH PELARGONIC ACID AND SPECIFIC ALS INHIBITORS BAYER CROPSCIENCE AG (DE) 2023-01-04 EP disclosed
US-20200368302-A1 PRODUCTION OF DUNALIELLA UNIVERSITY OF GREENWICH (GB) 2020-11-26 US disclosed
US-20200275652-A1 Synergistically Effective Herbicide Composition Comprising Pelargonic Acid and Flazasulfuron BELCHIM CROP PROTECTION NV (BE) 2020-09-03 US disclosed
EP-3488696-A1 HERBICIDAL COMBINATION WITH PELARGONIC ACID AND SPECIFIC ALS INHIBITORS Bayer CropScience Aktiengesellschaft (DE) 2019-05-29 EP disclosed
US-20060276342-A1 Herbicidal compositions BAYER CROPSCIENCE GMBH (DE) 2006-12-07 US disclosed
US-20060276337-A1 Oil suspension concentrate BAYER CROPSCIENCE GMBH (DE) 2006-12-07 US disclosed
US-20060111240-A1 Herbicidal compositions for tolerant or resistant maize crops BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-05-25 US disclosed
US-7012040-B2 Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous HOECHST SCHERING AGREVO GMBH (DE) 2006-03-14 US disclosed
EP-1113720-B1 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS FOR CONTROLLING HARMFUL PLANTS BAYER CROPSCIENCE GMBH (DE) 2006-01-11 EP disclosed
US-20050250647-A1 Herbicide combination BAYER CROPSCIENCE GMBH (DE) 2005-11-10 US disclosed
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-09-02 US disclosed
US-6723681-B2 HERBICIDE COMBINATIONS WITH AN EFFECTIVE CONTENT OF BROAD-SPECTRUM HERBICIDES FROM THE GROUP GLUFOSINATE (SALTS) AND RELATED COMPOUNDS, GLYPHOSATE (SALTS) AND RELATED COMPOUNDS, IMIDAZOLINONES, HERBICIDAL AZOLES HOECHST SCHERING AGREVO GMBH (DE) 2004-04-20 US disclosed
US-20030022792-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT CEREAL CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-01-30 US disclosed
US-20020094934-A1 Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous BAYER INTELLECTUAL PROPERTY GMBH (DE) 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111240-A1 Herbicidal compositions for tolerant or resistant maize crops PPOX, PNPO, DDO MEN1 3109/4885KMT2A 2671/4885F2 810/4885
US-20030022792-A1 HERBICIDAL COMPOSITIONS FOR TOLERANT OR RESISTANT CEREAL CROPS PPOX, PNPO, PAOX MEN1 3494/4885KMT2A 2459/4885F2 1512/4885
US-20230136215-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA MEN1 2166/4885KMT2A 3550/4885F2 3324/4885
US-20060276337-A1 Oil suspension concentrate PFAS, PNPO, PLPBP MEN1 4609/4885KMT2A 848/4885F2 1173/4885
US-20040171489-A1 Synergistic active compound combinations for controlling harmful plants L3MBTL4, TTL, EBPL MEN1 4434/4885KMT2A 793/4885F2 1011/4885
US-20200368302-A1 PRODUCTION OF DUNALIELLA DDT, DLD, DAGLA MEN1 2166/4885KMT2A 3550/4885F2 3324/4885
US-20020094934-A1 Glufosinates, glyphosates, imidazolinones, azoles of protoporphyrinogen oxidase inhibitors, cyclohexanediones, heteroaryloxyphenoxypropionic acids, and foliar- and soil-acting hebicides against mono- and di-cotyledonous PPOX, DDO, PNPO MEN1 3099/4885KMT2A 2919/4885F2 664/4885
US-20060276342-A1 Herbicidal compositions DDT, HDHD5, DGAT2 MEN1 4772/4885KMT2A 1141/4885F2 3973/4885
US-20240108008-A1 COMPOSITIONS COMPRISING MESOSULFURON-METHYL AND TEHP MTAP, AS3MT, HDHD5 MEN1 3621/4885KMT2A 764/4885F2 4722/4885
US-20050250647-A1 Herbicide combination DDT, MSRB3, MTX2 MEN1 2997/4885KMT2A 1243/4885F2 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.