Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MDH1 | P40925 | 5/20 | 0.38 |
| ▸ | MDH2 | P40926 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411772 | 0.87 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL20951293 | 0.82 | SHBG (0.53) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL8962181 | 0.80 | SHBG (0.52) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL24227113 | 0.77 | SHBG (0.48) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL465314 | 0.76 | SHBG (0.47) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL20926041 | 0.74 | SHBG (0.53) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL21017453 | 0.73 | SHBG (0.41) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL12190490 | 0.72 | ALDH1A1 (0.33) | CYP3A4SMN1; SMN2ALDH1A1HIF1AALOX15 | |
| SCHEMBL24775546 | 0.72 | TP53 (0.31) | TSHR | |
| SCHEMBL8962143 | 0.72 | ALDH1A1 (0.56) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015550-A1 | THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES | Covestro Deutschland AG (DE) | 2022-06-22 | — | — | EP | disclosed |