SCHEMBL465314

SCHEMBL465314

CC(C)(C)CC(C)(C)c1ccc(Nc2ccc(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.47
MAPT P10636 4/20 0.41
HPGD P15428 3/20 0.41
NR3C2 P08235 2/20 0.41
GAA P10253 2/20 0.41
RAB9A P51151 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 5/20 0.40
TSHR P16473 4/20 0.40
TDP1 Q9NUW8 4/20 0.40
SLC6A2 P23975 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALOX12 P18054 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
PTGS1 P23219 2/20 0.40
HTR2B P41595 2/20 0.40
ALOX15 P16050 2/20 0.40
MAPK1 P28482 1/20 0.40
PTGS2 P35354 1/20 0.40
CYP3A4 P08684 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962181 0.91 SHBG (0.52) SHBGMAPTHPGDNR3C2GAA
SCHEMBL411772 0.87 SHBG (0.59) SHBGMAPTHPGDNR3C2GAA
SCHEMBL20951293 0.85 SHBG (0.53) SHBGMAPTRAB9AALDH1A1TSHR
SCHEMBL42933 0.81 SHBG (0.60) SHBGMAPTTAAR1ALDH1A1TSHR
SCHEMBL24227113 0.81 SHBG (0.48) SHBGCYP3A4SMN1; SMN2MDH1MDH2
SCHEMBL7756284 0.79 ALDH1A1 (0.65) MAPTHPGDGAAALDH1A1TSHR
SCHEMBL21989958 0.79 ALDH1A1 (0.65) MAPTHPGDGAAALDH1A1TSHR
SCHEMBL8962143 0.79 ALDH1A1 (0.56) SHBGMAPTHPGDALDH1A1HSD17B10
SCHEMBL24520685 0.76 SHBG (0.47) SHBGMAPTHPGDGAARAB9A
SCHEMBL19985679 0.74 CYP3A4 (0.54) SHBGMAPTRAB9AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
CN-113755005-A Polyamide-based products 朗盛德国有限责任公司 2021-12-07 CN disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
EP-2553021-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-02-06 EP disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
WO-2012007301-A3 FOAM ENHANCEMENT OF FATTY ACYL GLYCINATE SURFACTANTS UNILEVER PLC (GB) 2012-05-10 WO disclosed
EP-2257597-B1 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2011-11-30 EP disclosed
US-7919013-B2 Thermoplastic moulding compositions with high stiffness BASF SE (DE) 2011-04-05 US disclosed
US-20100019210-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2010-01-28 US disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
EP-2049597-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2009-04-22 EP disclosed
WO-2008012233-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2008-01-31 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed