SCHEMBL8962181

SCHEMBL8962181

CC(C)(C)CC(C)(C)c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.52
ALDH1A1 P00352 7/20 0.50
ALOX12 P18054 5/20 0.50
HSD17B10 Q99714 4/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
ALOX15 P16050 3/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 2/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
MAPT P10636 8/20 0.49
HPGD P15428 3/20 0.49
GAA P10253 3/20 0.49
RAB9A P51151 1/20 0.49
CYP3A4 P08684 5/20 0.42
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411772 0.92 SHBG (0.59) SHBGALDH1A1ALOX12HSD17B10L3MBTL1
SCHEMBL465314 0.91 SHBG (0.47) SHBGALDH1A1ALOX12HSD17B10L3MBTL1
SCHEMBL20951293 0.86 SHBG (0.53) SHBGALDH1A1TSHRMAPK1MAPT
SCHEMBL8962143 0.83 ALDH1A1 (0.56) SHBGALDH1A1HSD17B10L3MBTL1MAPT
SCHEMBL9473731 0.82 ALDH1A1 (0.52) ALDH1A1ALOX12HSD17B10L3MBTL1ALOX15
SCHEMBL19985679 0.82 CYP3A4 (0.54) SHBGALDH1A1ALOX12HSD17B10ALOX15
SCHEMBL8373131 0.82 ALDH1A1 (0.61) SHBGALDH1A1HSD17B10ALOX15TSHR
SCHEMBL24227113 0.81 SHBG (0.48) SHBGCYP3A4SMN1; SMN2MDH1MDH2
SCHEMBL25989966 0.81 SHBG (0.48) SHBGMAPTHPGDGAARAB9A
SCHEMBL42933 0.81 SHBG (0.60) SHBGALDH1A1ALOX15TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2026-03-19 US claimed
EP-4514928-B1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2026-01-28 EP claimed
EP-4514928-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2025-03-05 EP claimed
EP-4007789-B1 CONTINUOUS PROCESS FOR THE POLYMERIZATION OR OLIGOMERIZATION OF DIPHENYLAMINES NYCO (FR) 2024-07-24 EP claimed
EP-4294874-B1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2024-04-03 EP claimed
EP-4294874-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2023-12-27 EP claimed
US-20230383060-A1 CONTINUOUS PROCESS FOR THE POLYMERIZATION OR OLIGOMERIZATION OF DIPHENYLAMINES NYCO (FR) 2023-11-30 US claimed
WO-2023209038-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2023-11-02 WO claimed
WO-2023209042-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2023-11-02 WO claimed
EP-4007789-A1 CONTINUOUS PROCESS FOR THE POLYMERIZATION OR OLIGOMERIZATION OF DIPHENYLAMINES NYCO (FR) 2022-06-08 EP claimed
EP-3704184-A1 ANTIOXIDANT POLYMERIC DIPHENYLAMINE COMPOSITIONS BASF SE (DE) 2020-09-09 EP claimed
CN-111278903-A Antioxidant polymeric diphenylamine compositions 巴斯夫欧洲公司 2020-06-12 CN claimed
US-20190127656-A1 LUBRICANT COMPOSITIONS COMPRISING POLYMERIC DIPHENYLAMINE ANTIOXIDANTS EXXONMOBIL RES & ENG CO (US) 2019-05-02 US claimed
US-20190127526-A1 Antioxidant Polymeric Diphenylamine Compositions BASF INTERSERVICIOS S.A. DE C.V. (MX) 2019-05-02 US claimed
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION NYCO (FR) 2026-03-19 US disclosed
WO-2025132964-A1 LUBRICANT COMPOSITIONS CONTAINING C8 DISUBSTITUTED DIPHENYLAMINE ANTIOXIDANT INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-26 WO disclosed
EP-4514928-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A LUBRICANT COMPOSITION NYCO (FR) 2025-03-05 EP disclosed
EP-0512950-A1 Substituted 1-aminonaphtalenes and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
US-5160647-A High temperature lubricants, heat and oxidation resistance CIBA-GEIGY CORPORATION (US) 1992-11-03 US disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078239-A1 USE OF AN ANTIOXIDANT FOR REDUCING AND/OR PREVENTING THE TOXICITY OF A RUBBER COMPOSITION GPX4, RAD50, POT1 SHBG 87/4885ALDH1A1 1197/4885ALOX12 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.