Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521577 | 0.88 | HDAC3 (0.49) | FFAR1MAPK14 | |
| SCHEMBL24521601 | 0.80 | GAA (0.54) | POLBL3MBTL1LMNA | |
| SCHEMBL24521556 | 0.80 | FFAR1 (0.59) | FFAR1FFAR4L3MBTL1NPC1RAB9A | |
| SCHEMBL29052272 | 0.79 | CTSS (0.51) | — | |
| SCHEMBL24521561 | 0.79 | CTSS (0.51) | — | |
| SCHEMBL15682713 | 0.76 | ERCC1 (0.68) | FFAR1FFAR4MAPK14L3MBTL1NPC1 | |
| SCHEMBL249436 | 0.75 | L3MBTL1 (0.61) | USP2POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL15682777 | 0.74 | NPC1 (0.59) | USP2POLBMAPK14L3MBTL1NPC1 | |
| SCHEMBL3578662 | 0.74 | BACE1 (0.56) | USP2POLBMAPK14L3MBTL1NPC1 | |
| SCHEMBL10757686 | 0.73 | ATM (0.51) | FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |