Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521577 | 0.83 | HDAC3 (0.49) | GAAEPHX2ALDH1A1KMT2AMEN1 | |
| SCHEMBL24521562 | 0.80 | FFAR1 (0.49) | POLBL3MBTL1LMNA | |
| SCHEMBL24521507 | 0.80 | EPHX2 (0.62) | GAAEPHX2POLBALDH1A1KMT2A | |
| SCHEMBL29052629 | 0.79 | SCN9A (0.53) | HDAC8 | |
| SCHEMBL24521600 | 0.79 | SCN9A (0.53) | HDAC8 | |
| SCHEMBL20380317 | 0.74 | LMNA (0.59) | EPHX2POLBALDH1A1TAOK1TAOK3 | |
| SCHEMBL24521598 | 0.73 | CYP3A4 (0.58) | EPHX2POLBKMT2AMEN1TAOK1 | |
| SCHEMBL24521599 | 0.73 | MEN1 (0.59) | EPHX2ALDH1A1KMT2AMEN1TAOK1 | |
| SCHEMBL23135875 | 0.72 | TAOK1 (0.53) | EPHX2ALDH1A1KMT2AMEN1TAOK1 | |
| SCHEMBL29562370 | 0.71 | ELANE (0.57) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |