Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24521562 | 0.88 | FFAR1 (0.49) | MAPK14FFAR1 | |
| SCHEMBL24521601 | 0.83 | GAA (0.54) | HDAC1HDAC8MEN1KMT2AALDH1A1 | |
| SCHEMBL24521503 | 0.78 | MTOR (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL30791534 | 0.78 | TRPV1 (0.63) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL22547959 | 0.77 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL29052292 | 0.77 | CTSS (0.53) | HDAC8PPARA | |
| SCHEMBL24521579 | 0.77 | CTSS (0.53) | HDAC8PPARA | |
| SCHEMBL4574985 | 0.75 | LSS (0.52) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL29059895 | 0.75 | ELANE (0.57) | KMT2AALDH1A1FFAR1PPARAELANE | |
| SCHEMBL29562370 | 0.75 | ELANE (0.57) | FFAR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015501-A1 | N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-06-22 | — | — | EP | disclosed |