Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784155 | 0.85 | ALOX5AP (0.49) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL7205617 | 0.83 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL27784746 | 0.80 | PARP10 (0.38) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL27397264 | 0.79 | NPC1 (0.46) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL16738874 | 0.79 | ALOX5AP (0.48) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL11053117 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HSD17B10TDP1KMT2ACYP3A4 | |
| SCHEMBL141445 | 0.78 | HSD17B10 (0.50) | ALDH1A1HSD17B10PDE4BPDE4APDE4C | |
| Tannin Pyrogallol SCHEMBL7671493 | 0.77 | HSD17B10 (0.50) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL3791228 | 0.77 | ALDH1A1 (0.56) | ALOX5APFEN1ALDH1A1HSD17B10PDE4B | |
| SCHEMBL6834129 | 0.76 | HSD17B10 (0.48) | ALDH1A1HSD17B10PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4016656-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | Samsung Electronics Co., Ltd. (KR) | 2022-06-22 | — | — | EP | disclosed |
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |