SCHEMBL6834129

SCHEMBL6834129

Cc1c(-c2ccccc2)ccc(N)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 2/20 0.48
POLB P06746 1/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
PARP10 Q53GL7 1/20 0.42
PARP11 Q9NR21 1/20 0.42
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42
PDE3B Q13370 1/20 0.42
PDE3A Q14432 1/20 0.42
ESR2 Q92731 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CD44 P16070 1/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2B6 P20813 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL17969155 0.98 HSD17B10 (0.46) HSD17B10ALDH1A1POLBPDCD1CD274
SCHEMBL141445 0.84 HSD17B10 (0.50) HSD17B10ALDH1A1PDCD1CD274PARP10
SCHEMBL3976631 0.84 LTA4H (0.41) HSD17B10ALDH1A1POLBPDCD1CD274
SCHEMBL10935618 0.83 POLB (0.67) HSD17B10ALDH1A1POLBPDCD1CD274
SCHEMBL28845278 0.83 HSD17B10 (0.48) HSD17B10ALDH1A1POLBPDCD1CD274
SCHEMBL19362007 0.81 CES2 (0.49) MAPTTDP1
SCHEMBL9285276 0.81 POLB (0.62) ALDH1A1POLBMAOAMAOBCD44
SCHEMBL2224612 0.79 ALDH1A1 (0.54) HSD17B10ALDH1A1PDE4APDE4BPDE4C
SCHEMBL28874443 0.79 ESR2 (0.46) HSD17B10ALDH1A1PDCD1CD274PARP10
SCHEMBL28874324 0.79 BACE1 (0.46) HSD17B10ALDH1A1POLBPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829747-B2 Liquid crystal display panel and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US claimed
US-20150205167-A1 LIQUID CRYSTAL DISPLAY PANEL AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISLAY CO., LTD. (KR) 2015-07-23 US claimed
EP-0919851-B1 METHOD FOR LIQUID CRYSTAL ALIGNMENT NISSAN CHEMICAL IND LTD (JP) 2003-10-22 EP claimed
US-6063829-A Method for liquid crystal alignment NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-16 US claimed
EP-0540829-B1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL IND LTD (JP) 1997-02-26 EP claimed
US-5298590-A Polyamide resin consisting diamine including aromatic diamine having at least one linear alkyl group NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-03-29 US claimed
EP-0540829-A1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-05-12 EP claimed
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-17 US disclosed
US-9981914-B2 2018-05-29 US disclosed
US-20180086717-A1 HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT TOKYO OHKA KOGYO CO., LTD. (JP) 2018-03-29 US disclosed
US-9829747-B2 Liquid crystal display panel and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-28 US disclosed
US-20150205167-A1 LIQUID CRYSTAL DISPLAY PANEL AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISLAY CO., LTD. (KR) 2015-07-23 US disclosed
US-20040062878-A1 Aligning agent for liquid crystal for in-plane switching, liquid-crystal alignment film, and liquid-crystal display element MANO YUICHI (JP) 2004-04-01 US disclosed
EP-0919851-B1 METHOD FOR LIQUID CRYSTAL ALIGNMENT NISSAN CHEMICAL IND LTD (JP) 2003-10-22 EP disclosed
EP-1331510-A1 ALIGNING AGENT FOR LIQUID CRYSTAL FOR IN-PLANE SWITCHING, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT Nissan Chemical Industries, Ltd. (JP) 2003-07-30 EP disclosed
US-6063829-A Method for liquid crystal alignment NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-16 US disclosed
EP-0919851-A1 METHOD FOR LIQUID CRYSTAL ALIGNMENT NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-06-02 EP disclosed
EP-0540829-B1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL IND LTD (JP) 1997-02-26 EP disclosed
US-5298590-A Polyamide resin consisting diamine including aromatic diamine having at least one linear alkyl group NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1994-03-29 US disclosed
EP-0540829-A1 Novel liquid crystal alignment treating agent NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1993-05-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086717-A1 HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT SLC9A2, SLC9A1, NHERF1 HSD17B10 794/4885ALDH1A1 3686/4885POLB 2120/4885
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element SLC9A2, SLC9A1, NHERF1 HSD17B10 794/4885ALDH1A1 3686/4885POLB 2120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.