SCHEMBL24523720

SCHEMBL24523720

N#Cc1ccc2c3cc4c(oc5ccc6ccccc6c54)c4c5ccc(C#N)cc5n(c2c1)c34

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
ENPP3 O14638 1/20 0.37
CDY1; CDY1B Q9Y6F8 2/20 0.36
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MYB P10242 1/20 0.33
PDPK1 O15530 1/20 0.32
CBX7 O95931 1/20 0.32
CDYL2 Q8N8U2 1/20 0.32
CDYL Q9Y232 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24523825 0.86 TNKS (0.37) CA1CA2KDM4EALDH1A1MEN1
SCHEMBL24523784 0.85 ENPP3 (0.35) CA1CA2ENPP3CDY1; CDY1B
SCHEMBL24523828 0.85 CDY1; CDY1B (0.36) CA1CA2KDM4EALDH1A1ENPP3
SCHEMBL24524318 0.83 KMO (0.30)
SCHEMBL24523833 0.82 TNKS (0.39) KDM4EALDH1A1MEN1CYP3A4GAA
SCHEMBL24523767 0.82 CA1 (0.46) CA1CA2KDM4EALDH1A1CYP1A2
SCHEMBL24523806 0.82 ENPP3 (0.32) ENPP3
SCHEMBL24523718 0.79 ACLY (0.34) ALDH1A1ENPP3PRKDC
SCHEMBL24523749 0.76 ENPP3 (0.39) CA1CA2KDM4EALDH1A1GAA
SCHEMBL24523819 0.75 ENPP3 (0.35) CA1CA2ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed