SCHEMBL24523735

SCHEMBL24523735

CC(C)c1cc(C#N)cc2c1c1cccc3c4c(C(C)C)cc(C#N)cc4n2c13

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD1 O95696 1/20 0.31
BRPF1 P55201 1/20 0.31
BRPF3 Q9ULD4 1/20 0.31
ALK Q9UM73 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24524241 0.85 BRD1 (0.31) BRD1BRPF1BRPF3
SCHEMBL24523774 0.77 CYP1A2 (0.34)
SCHEMBL24524240 0.74 BRD1 (0.37) BRD1BRPF1
SCHEMBL24523908 0.73 METAP2 (0.43)
SCHEMBL24523742 0.73 IMPDH2 (0.34)
SCHEMBL24523737 0.72 IMPDH2 (0.35)
SCHEMBL24523753 0.71 METAP2 (0.41)
SCHEMBL24523764 0.70 METAP2 (0.40)
SCHEMBL24523770 0.69 IMPDH2 (0.38)
SCHEMBL24528141 0.69 NFATC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed