Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524247 | 0.85 | IMPDH2 (0.31) | IMPDH2AR | |
| SCHEMBL24523725 | 0.80 | IMPDH2 (0.38) | IMPDH2MAOAKDM4EALDH1A1GAA | |
| SCHEMBL24523738 | 0.76 | TRPV4 (0.38) | IMPDH2MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL24523742 | 0.75 | IMPDH2 (0.34) | IMPDH2IMPDH1MAOAKDM4EALDH1A1 | |
| SCHEMBL24524244 | 0.74 | MAP4K1 (0.37) | IMPDH2ARALDH1A1 | |
| SCHEMBL24523744 | 0.73 | AR (0.44) | AR | |
| SCHEMBL24523907 | 0.73 | MAOA (0.40) | IMPDH2MAOAKDM4EALDH1A1GAA | |
| SCHEMBL24523735 | 0.72 | BRD1 (0.31) | — | |
| SCHEMBL24523770 | 0.70 | IMPDH2 (0.38) | IMPDH2IMPDH1MAOAKDM4EALDH1A1 | |
| SCHEMBL24523906 | 0.70 | IMPDH2 (0.38) | IMPDH2IMPDH1ARKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |